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Superantigen
Written by NCI Thesaurus v.07.09d   
Definition of Superantigen
Microbial antigens that have in common an extremely potent activating effect on T-cells that bear a specific variable region. Superantigens cross-link the variable region with class II MHC proteins regardless of the peptide binding in the T-cell receptor's pocket. The result is a transient expansion and subsequent death and anergy of the T-cells with the appropriate variable regions.

Superantigen is from the group

Toxin

Other Names for Superantigen

Superantigen

Source

NCI Thesaurus License

 
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