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Haloperidol
Written by NCI Thesaurus v.07.09d   
Definition of Haloperidol
A phenylbutylpiperadine derivative with antipsychotic, neuroleptic and antiemetic effects. Haloperidol competitively blocks postsynaptic dopamine (D2) receptors in the mesolimbic system of the brain, thereby eliminating dopamine neurotransmission and leading to antidelusionary and anti-hallucinogenic effects. The antagonistic activity mediated through D2 dopamine receptors in the chemoreceptive trigger zone (CTZ) accounts for its antiemetic activity.

Haloperidol is from the group

Butyrophenone

Other Names for Haloperidol

Haloperidol
4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone
HALOPERIDOL
Haldol
McN-JR-1625
R 1625
R-1625

Source

NCI Thesaurus License

 
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