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Etanercept
Written by NCI Thesaurus v.07.09d   
Definition of Etanercept
A recombinant soluble dimeric fusion protein consisting of the extracellular ligand-binding region of recombinant human tumor necrosis factor (rhTNF) receptor attached to the constant (Fc) region of human immunoglobulin G (FcIgG). The receptor moiety of etanercept binds to circulating TNF (2 molecules of TNF per receptor) and inhibits its attachment to endogenous TNF cell surface receptors, thereby rendering TNF inactive and inhibiting TNF-mediated mechanisms of inflammation. (NCI04)

Etanercept is from the group

Immunosuppressant

Other Names for Etanercept

Etanercept
Enbrel
TNFR:Fc
Tumor Necrosis Factor Receptor IgG Chimera

Source

NCI Thesaurus License

 
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