Advertisement

Syndicate

Physician Resources Home arrow Medical News arrow Thyrotropin levels may be associated with coronary heart disease in women
Thyrotropin levels may be associated with coronary heart disease in women
Written by NetDoc.com Medical News Feed   

CHICAGO—Women with increasing levels of thyrotropin within the normal range appear to have a higher risk of fatal coronary heart disease, according to a report in the April 28 issue of the JAMA/Archives journals.

Discuss this article on the forums. (0 posts)

 

 

Thyrotropin, a hormone produced by the pituitary gland, is released into the blood and acts on the thyroid gland to stimulate its growth and function, according to background information in the article. “Emerging evidence indicates that levels of thyrotropin within the reference [normal] range are positively and linearly associated with systolic [top number] and diastolic [bottom number] blood pressure, body mass index and serum lipid concentrations with adverse effects on cardiovascular health.”

Bjørn O. Åsvold, M.D., of the Norwegian University of Science and Technology, Trondheim, Norway, and colleagues studied the association between thyrotropin levels and fatal heart disease in 17,311 women and 8,002 men without known thyroid disease, cardiovascular disease or diabetes at the beginning of the study.

During follow-up, 228 women (1.3 percent) and 182 men (2.3 percent) had died of coronary heart disease. “Of these, 192 women and 164 men had thyrotropin levels within the clinical reference range of 0.5 milli-international units per liter to 3.5 milli-international units per liter,” the authors write. “Overall, thyrotropin levels within the reference range were positively associated with coronary heart disease mortality; the trend was statistically significant in women but not in men.”

“This study shows that coronary heart disease mortality increases in women with increasing levels of thyrotropin within the reference range,” the authors conclude. “These results indicate that relatively low but clinically normal thyroid function may increase the risk of fatal coronary heart disease.”
(Arch Intern Med. 2008;168[8]:855-860.

Editor's Note: This study was supported by the Norwegian University of Science and Technology and by the Central Norway Regional Health Authority. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

For more information, contact JAMA/Archives media relations at 312/464-JAMA (5262) or e-mail mediarelations{at}jama-archives.org .

Discuss this article on the forums. (0 posts)

 
< Prev   Next >

Common Diseases

Swine Flu - Updates and information on H1N1 2009 (AKA Swine Influenza) pandemic.

Ankylosing spondylitis - Current protocols for diagnosis and treatment options.

Wegener granulomatosis - Autoimmune etiology and clinical course.

Diabetes - disease and management information, including diagnosis, typical treatment plans and diabetes supplies.

Advertisement

Medical Careers

The US medical jobs market has stayed hot for health care providers. Whether you believe that a provider shortage is in the offing or that the ratio of physicians-to-patients is too high, physician jobs and nursing jobs abound.

A wide variety of medical jobs can be found in the netdoc health care job listings. Particular strengths include permanent and locum tenens physician jobs, nursing jobs across the US, and radiology positions.

Other resources include physician salary information, medical career guidance, and the ability to post physician jobs.

Polls

When hiring your medical practice office manager, what was the most important consideration?
 
Copyright 2005 - 2019 Medical Resource Group, LLC. All rights reserved.