Physician Resources Home arrow Medical News arrow Statins Lower Morbidity and Mortality
Statins Lower Morbidity and Mortality
Written by Jeanne Bohm, Ph.D.   

From the NetDoc medical news feed

Heart failure patients treated initially with statins had a 25 percent reduced risk of death, as well as a lower risk for hospitalization, according to a study described in the November 1 issue of JAMA.

Alan S. Go, M.D., Kaiser Permanente of Northern California,and colleagues examined the relationship between statin therapy and associated risks including death and other complications in patients with heart failure who were eligible for lipid-lowering therapy.

Statins have been shown to effectively lower low-density lipoprotein (LDL) cholesterol levels. However, complications of statin treatment include a higher risk of adverse events in patients with heart failure and low LDL cholesterol levels.

The study (1996 - 2004) included 24,598 adults, approximately half of the participants (n = 12,648) initiated statin therapy. The study followed the patients for a median of 2.4 years after initiation of statin. During the followup period, 8,235 patients died.

The data showed that patients initially using statin had a 24 percent lower relative risk of death (14.5 deaths per 100 person-years compared with not taking a statin (25.3 deaths per 100 person-years). Adjustments of the analysis included the patient's cholesterol level and concomitant cardiovascular medications. Statin use was also associated with a 21 percent lower relative risk of hospitalization for heart failure. The correlation between lower risks for death and hospitalization were evident regardless of the presence of known coronary heart disease.

The researchers concluded that further study of the role of statins in patients with nonischemic heart failure who do not receive lipid-lowering therapy as part of their treatment protocol are needed. 


Statin Therapy and Risks for Death and Hospitalization in Chronic Heart Failure. JAMA. 2006;296:2105-2111. 
JAMA Press Release 

About the Author

Jeanne Bohm, Ph.D. is a cancer biologist by training, a medical writer and an experienced science educator.

The author has no financial relationship to any of the companies listed in the article.


< Prev   Next >

Common Diseases

Swine Flu - Updates and information on H1N1 2009 (AKA Swine Influenza) pandemic.

Ankylosing spondylitis - Current protocols for diagnosis and treatment options.

Wegener granulomatosis - Autoimmune etiology and clinical course.

Diabetes - disease and management information, including diagnosis, typical treatment plans and diabetes supplies.


Medical Careers

The US medical jobs market has stayed hot for health care providers. Whether you believe that a provider shortage is in the offing or that the ratio of physicians-to-patients is too high, physician jobs and nursing jobs abound.

A wide variety of medical jobs can be found in the netdoc health care job listings. Particular strengths include permanent and locum tenens physician jobs, nursing jobs across the US, and radiology positions.

Other resources include physician salary information, medical career guidance, and the ability to post physician jobs.


When hiring your medical practice office manager, what was the most important consideration?
Copyright 2005 - 2019 Medical Resource Group, LLC. All rights reserved.