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Vinblastine
Written by NCI Thesaurus v.07.09d   
Definition of Vinblastine
A natural alkaloid isolated from the plant Vinca rosea Linn. Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the M phase of the cell cycle. This agent may also interfere with amino acid, cyclic AMP, and glutathione metabolism -- calmodulin-dependent Ca++ -transport atpase activity -- cellular respiration -- and nucleic acid and lipid biosynthesis. (NCI04)

Vinblastine is from the group

Vinca-Site Binding Agent
Vinca Alkaloid Compound

Other Names for Vinblastine

Vinblastine
VINBLASTINE
VLB
Vincaleucoblastine
vinblastine

Source

NCI Thesaurus License

 
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