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Physician Resources Home arrow Medical Dictionary arrow Urinary Bladder Tumor Antigen
Urinary Bladder Tumor Antigen
Written by NCI Thesaurus v.07.09d   
Definition of Urinary Bladder Tumor Antigen
Bladder tumor associated antigen is a human complement factor H-related protein (hCFHrp), a glycoprotein produced by cancer cells and macrophages but not by normal epithelia. In cell culture, hCFHrp was shown to be produced by several human bladder cancer cell lines, but not by normal epithelial cell lines. By interaction with complement factor C3b, hCFH serves to inhibit the formation of a membrane attack complex, thereby preventing cell lysis. Production of bladder tumor associated antigen may confer a selective growth advantage to cancer cells in vivo by allowing the cells to evade the host immune system. approved by FDA as a tumor marker for screening test for transitional cell carcinoma.

Urinary Bladder Tumor Antigen is from the group

Tumor Antigen

Other Names for Urinary Bladder Tumor Antigen

Urinary Bladder Tumor Antigen
BTA

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NCI Thesaurus License

 
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