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LGD 1550
Written by NCI Thesaurus v.07.09d   
Definition of LGD 1550
An orally-active synthetic aromatic retinoic acid agent with potential antineoplastic and chemopreventive activities. LGD 1550 selectively binds to all three retinoic acid receptors (RAR-alpha, RAR-beta, and RAR-gamma), resulting in alterations in the expression of genes responsible for cell differentiation and proliferation. This agent also acts as an inhibitor of activator protein 1 (AP-1), a protein that mediates trophic responses and malignant transformation. (NCI04)

LGD 1550 is from the group

Retinoic Acid Agent

Other Names for LGD 1550

LGD 1550
(2E,4E,6E)-7-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-methyl-2,4,6-octatrienoic Acid

Source

NCI Thesaurus License

 
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