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Integrin
Written by NCI Thesaurus v.07.09d   
Definition of Integrin
Integrins are transmembrane glycoprotein receptors that mediate cell-matrix or cell-cell adhesion, and transduce signals that regulate gene expression and cell growth. They are heterodimeric molecules consisting of noncovalently linked alpha and beta subunits. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Both alpha and beta subunits display a cytoplasmic domain that interacts with the cytoskeleton (and possibly signaling molecules), a transmembrane region, and a large extracellular domain that interacts with the extracellular matrix. (from OMIM 147557)

Integrin is from the group

RGD Receptor

Other Names for Integrin

Integrin
Extracellular Matrix, Integrins

Source

NCI Thesaurus License

 
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