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Disulfiram
Written by NCI Thesaurus v.07.09d   
Definition of Disulfiram
A carbamoyl derivate used in the treatment of alcoholism. Disulfiram irreversibly inhibits acetaldehyde dehydrogenase that oxidizes the ethanol metabolite acetaldehyde into acetic acid. This leads to an accumulation of acetaldehyde that produces a variety of very unpleasant symptoms referred to as the disulfiram-alcohol reaction. This reaction includes , but is not limited to, flushing, headache, respiratory difficulty, nausea,vomiting, sweating, thirst, chest pain, tachycardia, blurred vision and hypotension.

Disulfiram is from the group

Angiogenesis Inhibitor
Multidrug Resistance Modulator

Other Names for Disulfiram

Disulfiram
Antabuse
Bis(diethylthiocarbamoyl) Disulfide
DISULFIRAM
DS
TTD
Tetraethylthioperoxydicarbonic Diamide
Tetraethylthiuram Disulfide
Teturamin
disulfiram

Source

NCI Thesaurus License

 
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