Written by NCI Thesaurus v.07.09d   
Definition of Disulfiram
A carbamoyl derivate used in the treatment of alcoholism. Disulfiram irreversibly inhibits acetaldehyde dehydrogenase that oxidizes the ethanol metabolite acetaldehyde into acetic acid. This leads to an accumulation of acetaldehyde that produces a variety of very unpleasant symptoms referred to as the disulfiram-alcohol reaction. This reaction includes , but is not limited to, flushing, headache, respiratory difficulty, nausea,vomiting, sweating, thirst, chest pain, tachycardia, blurred vision and hypotension.

Disulfiram is from the group

Angiogenesis Inhibitor
Multidrug Resistance Modulator

Other Names for Disulfiram

Bis(diethylthiocarbamoyl) Disulfide
Tetraethylthioperoxydicarbonic Diamide
Tetraethylthiuram Disulfide


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