CD166 Antigen
Written by NCI Thesaurus v.07.09d   
Definition of CD166 Antigen
ALCAM is a cell adhesion molecule expressed on mitogen-activated leukocytes and monocytes, fibroblasts, neurons, and tumor-derived cell lines but not on unactivated leukocytes. ALCAM is a ligand for CD6, a receptor expressed on T-cells involved in cell adhesion interactions between thymocytes and thymic epithelial cells. ALCAM/CD6 interactions may play a role in the binding of T- and B-cells to activated leukocytes. ALCAM has five Ig domains and its amino acid sequence has significant homology to chicken neural adhesion molecule BEN/SC-1/DM-GRASP. (from OMIM 601662 and NCI)

CD166 Antigen is from the group

Cell Adhesion Molecule

Other Names for CD166 Antigen

CD166 Antigen
Activated Leukocyte Cell Adhesion Molecule
CD6 Ligand


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