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Bacampicillin
Written by NCI Thesaurus v.07.09d   
Definition of Bacampicillin
A prodrug of ampicillin, a broad-spectrum, semisynthetic, beta-lactam aminopenicillin antibiotic with bactericidal activity. Bacampicillin is hydrolyzed in vivo by esterases to its active metabolite ampicillin. ampicillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.

Bacampicillin is from the group

Penicillin Antibiotic

Other Names for Bacampicillin

Bacampicillin
BACAMPICILLIN

Source

NCI Thesaurus License

 
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