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BRCA2 Mutation
Written by NCI Thesaurus v.07.09d   
Definition of BRCA2 Mutation
A mutation that is typically a heritable, permanent change in the nucleotide sequence of the BRCA2 gene. single nucleotide substitutions and small deletions or insertions (1-20 bases) account for the majority of mutations in the BRCA2 gene. Most of these alterations result in a truncated form of the breast cancer type 2 susceptibility protein. Mutations in the BRCA2 gene predispose males to breast cancer.

BRCA2 Mutation is from the group

Gene Abnormality

Other Names for BRCA2 Mutation

BRCA2 Mutation
Mutation of the BRCA2 Gene

Source

NCI Thesaurus License

 
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