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Transformation
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Written by NCI Thesaurus v.07.09d   
Definition of Transformation
The conversion of a cell from a normal phenotype, which undergoes a limited number of mitotic divisions, into an aberrant phenotype that is immortal and divides indefinitely. Transformed cells no longer retain cell-cycle checkpoints and may ultimately become malignant cancer cells via additional genetic mutations, or damaging environmental events.

Transformation is from the group

Tumor Initiation

Other Names for Transformation

Transformation
Cell Transformation
Cellular Transformation
Transformed
Transforming
transformation

Source

NCI Thesaurus License

 
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