Mutation Written by NCI Thesaurus v.07.09d   

Definition of Mutation Permanent, transmissible changes in the genetic material of an organism. Mutations can range from a single base change to the loss of a significant portion of a chromosome. These occur when DNA is not repaired prior to replication. Mutations in germ cells can be inherited. However, in somatic cells, they are not inherited. Somatic mutations can arise via exposure to chemical mutagens or ionizing radiation. These fixed changes in the genetic material can, in some cases, lead to cancer or other diseases. Mutation is from the group DNA Sequence Alteration Other Names for Mutation Mutation Genetic Alteration Genetic Change Mutated mutation Source NCI Thesaurus License

 

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