Lisinopril Written by NCI Thesaurus v.07.09d   

Definition of Lisinopril A synthetic peptide derivate and long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Lisinopril specifically and competitively inhibits angiotensin-converting enzyme thereby decreasing the formation of the potent vasoconstrictor angiotensin II. This leads to a diminished vasopressor activity. In addition, angiotensin II-stimulated aldosterone secretion by adrenal cortex is decreased which results in a decrease of sodium and water retention and an increase of serum potassium. Lisinopril is from the group ACE Inhibitor Antihypertensive Agent Other Names for Lisinopril Lisinopril LISINOPRIL N2-[(1S)-1-Carboxy-3-phenylpropyl]-L-lysyl-L-proline, Dihydrate Prinivil Zestril Source NCI Thesaurus License

 

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