Kanamycin Written by NCI Thesaurus v.07.09d   

Definition of Kanamycin An aminoglycoside antibiotic with antimicrobial property. amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically in contact with 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and, misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used for treatment of E. coli, Proteus species (both indole-positive and indole-negative), E. aerogenes, K. pneumoniae, S. marcescens, and Acinetobacter species. Kanamycin is from the group Aminoglycoside Antibiotic Other Names for Kanamycin Kanamycin KANAMYCIN Source NCI Thesaurus License

 

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