Graft Versus Host Disease
Written by NCI Thesaurus v.07.09d
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Definition of Graft Versus Host Disease | An incompatibility reaction (which may be fatal) in a subject (host) of low immunological competence (deficient lymphoid tissue) who has been the recipient of immunologically competent lymphoid tissue from a donor who lacks at least one antigen possessed by the recipient host -- the reaction, or disease, is the result of action of the transplanted cells against those host tissues that possess the antigen not possessed by the donor. Seen most commonly following bone marrow transplantation, acute disease is seen after 5-40 days and chronic disease weeks to months after transplantation, affecting, principally, the gastrointestinal tract, liver, and skin. Graft Versus Host Disease is from the group Cancer-Related Condition Transplant-Related Disorder
Other Names for Graft Versus Host Disease Graft Versus Host Disease GVHD Graft Vs. Host Disease Graft vs Host Disease Graft-Versus-Host-Disease Runt Disease graft-versus-host disease
Source NCI Thesaurus License
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