| A synthetic nucleoside analogue of deoxyadenosine in which the 3' hydroxyl on the ribose moiety is replaced by a hydrogen atom. In vivo, didanosine is converted to the active triphosphate form, which is incorporated into DNA. The absence of the 3' hydroxyl inhibits DNA elongation because phosphodiester bonds cannot be made with the substituted hydrogen. (NCI04) Didanosine is from the group Reverse Transcriptase Inhibitor
Other Names for Didanosine
Didanosine
2',3'-Dideoxyinosine
DIDANOSINE
Didanosine EC
Dideoxyinosine
Videx
Videx EC
ddI
didanosine
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