| A mixture of glycopeptide antineoplastic antibiotics isolated from the fungus streptomyces verticillus. Bleomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA -- these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation. (NCI04) Bleomycin is from the group Bleomycin Antibiotic
Other Names for Bleomycin
Bleomycin
BLEO
BLEOMYCIN
BLM
Bleo
bleomycin
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