CHICAGO—The common practice of administering heparin soon after cardioembolic stroke is associated with an increased risk for serious bleeding, according to an article posted online today that will appear in the September 2008 print issue of Archives of Neurology, one of the JAMA/Archives journals. However, it appears that anticoagulation with warfarin therapy may safely begin shortly after stroke.

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Washington, DC   July 8, 2008  The chemical dopamine induces both desire and dread, according to new animal research in the July 9 issue of The Journal of Neuroscience. Although dopamine is well known to motivate animals and people to seek positive rewards, the study indicates that it also can promote negative feelings like fear. The finding may help explain why dopamine dysfunction is implicated not only in drug addiction, which involves excessive desire, but in schizophrenia and some phobias, which involve excessive fear.

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CHICAGO—A therapy that involves depriving the prostate gland the male hormone androgen is not associated with improved survival for elderly men with localized prostate cancer, compared to conservative management of the disease, according to a study in the July 9 issue of JAMA.

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CHICAGO—Despite concerns that reductions in physician reimbursements for outpatient chemotherapy related drugs as a result of the Medicare Modernization Act of 2003 would have a detrimental effect on patients requiring chemotherapy, new research indicates that there have not been major changes in travel distance and patient wait times for chemotherapy in the Medicare population since 2003, according to a study in the July 9 issue of JAMA.

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