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Zalcitabine

Written by NCI Thesaurus v.07.09d

Definition of Zalcitabine

A synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zalcitabine preferentially inhibits the gamma form of dna polymerase present in tumor cell mitochondria, resulting in the inhibition of tumor cell mitochondrial dna replication and tumor cell death. (NCI04)

Zalcitabine is from the group

Pyrimidine Antagonist

Other Names for Zalcitabine

Zalcitabine
2',3'-Dideoxycytidine
Dideoxycytidine
Hivid
ZALCITABINE
ddC

Source

NCI Thesaurus License

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