Therapeutic Interleukin-4 Written by NCI Thesaurus v.07.09d   

Definition of Therapeutic Interleukin-4 A recombinant agent chemically identical to or similar to the endogenous cytokine interleukin-4 (IL-4). Produced primarily by activated T-cells, IL-4 binds to and activates its cell-surface receptor, stimulating the proliferation and differentiation of activated B-cells and enhancing their ability to present antigens to T-cells. As a potential immunotherapeutic agent, recombinant IL-4 also augments the effects of other cytokines on dendritic cells (DC), cytotoxic T lymphocytes (CTL), and tumor-infiltrating lymphocytes (TIL). Therapeutic Interleukin-4 is from the group Therapeutic Interleukin Other Names for Therapeutic Interleukin-4 Recombinant Interleukin-4 B Cell Proliferating Factor B-Cell Growth Factor B-Cell Stimulating Factor B-Cell Stimulatory Factor 1 BCGF BCSF 1 IL-4 Interleukin-4 MCGF 2 Mast Cell Growth Factor-2 RHIL-4 Recombinant Human IL-4 T-Cell Growth Factor 2 interleukin-4 Source NCI Thesaurus License

 

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