| An aminoglycoside antibiotic isolated from the bacterium streptomyces alboniger. Acting as an analog of the 3' terminal end of aminoacyl-tRNA, puromycin incorporates itself into a growing polypeptide chain and causes its premature termination, thereby inhibiting protein synthesis. This agent has antimicrobial, antitrypanosomal, and antineoplastic properties -- it is used as an antibiotic in cell culture. (NCI04) Puromycin is from the group Miscellaneous Antineoplastic Antibiotic Protein Synthesis Inhibitor
Other Names for Puromycin Puromycin Adenosine, 3'-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3'-deoxy-N,N-dimethyl-, (S)- Adenosine, 3'-(alpha-amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyl-, L- CL 16536 L-3'-(alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine P-638 Puromicina Puromycine Puromycinum Stillomycin Stylomycin
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