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Monoclonal Antibody ABX-CBL
Written by NCI Thesaurus v.07.09d   
Definition of Monoclonal Antibody ABX-CBL
A murine igm monoclonal antibody (MoAb) developed for the potential treatment of graft versus host disease (GvHD). MoAb ABX-CBL recognizes human CD147 antigen, weakly expressed on human leukocytes and up-regulated on activated lymphocytes. This MoAb is capable of neutralizing inflammatory reactions via a complement-dependent cytotoxic mechanism. However, MoAb ABX-CBL does not offer an improvement over antithymocyte globulin in the treatment of acute steroid resistant GVHD.

Monoclonal Antibody ABX-CBL is from the group

Monoclonal Antibody

Other Names for Monoclonal Antibody ABX-CBL

Monoclonal Antibody ABX-CBL
Gavilimomab

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NCI Thesaurus License

 
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