Fluconazole Written by NCI Thesaurus v.07.09d   

Definition of Fluconazole A synthetic triazole with antifungal activity. Fluconazole preferentially inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols, the loss of normal fungal sterols, and fungistatic activity. mammalian cell demethylation is much less sensitive to fluconazole inhibition. Fluconazole is from the group Antifungal Agent Other Names for Fluconazole Fluconazole Diflucan FLUCONAZOLE alpha-(2,4-difluorophenyl)-alpha- (1,2,4-triazol-1-ylmethyl)-1,2, 4- triazole-1-ethanol fluconazole Source NCI Thesaurus License

 

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