| A semisynthetic estrogen. Ethinyl estradiol binds to the estrogen receptor complex and enters the nucleus, activating DNA transcription of genes involved in estrogenic cellular responses. This agent also inhibits 5-alpha reductase in epididymal tissue, which lowers testosterone levels and may delay progression of prostatic cancer. In addition to its antineoplastic effects, ethinyl estradiol protects against osteoporosis. In animal models, short-term therapy with this agent has been shown to provide long-term protection against breast cancer, mimicking the antitumor effects of pregnancy. (NCI04) Ethinyl Estradiol is from the group Therapeutic Estradiol
Other Names for Ethinyl Estradiol Ethinyl Estradiol (17alpha)-19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol Diogyn E Diogyn-E ETHINYL ESTRADIOL Estinyl Ethinoral Ethinylestradiol Eticylol Feminone Inestra Lynoral Orestralyn
Source NCI Thesaurus License
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