| A synthetic nucleoside analogue of deoxyadenosine and a prodrug of didanosine in which the 3' hydroxyl group on the ribose moiety is replaced by a hydrogen atom. Dideoxyadenosine competitively inhibits adenylyl cyclase, thereby reducing levels of cyclic adenosine monophosphate (cAMP). By inhibiting cAMP-mediated gene activation in tumor cells, this agent may retard tumor cell proliferation. (NCI04) Dideoxyadenosine is from the group Nucleoside
Reverse Transcriptase Inhibitor
Other Names for Dideoxyadenosine
Dideoxyadenosine
2',3'-Dideoxyadenosine
6-Amino-9-(2''3'-dideoxy-beta-D-glycero-pentofuranosyl)purine
ddA
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