NetDoc - Diazoxide

Diazoxide

Written by NCI Thesaurus v.07.09d

Definition of Diazoxide

A benzothiadiazine derivate with antihypertensive and hyperglycemic activities. Diazoxide increases membrane permeability to potassium ions in vascular smooth muscle, thereby stabilizing the membrane action potential and preventing vascular smooth muscle contraction -- this results in peripheral vasodilatation and decreases in peripheral vascular resistance. This agent also inhibits insulin release by interacting with ATP-sensitive potassium channels of pancreatic islet beta-cells.

Diazoxide is from the group

Vasodilating Agent

Other Names for Diazoxide

Diazoxide
3-Methyl-7-chloro-1,2,4-benzothiadiazine 1,1-Dioxide
DIAZOXIDE
Proglycem
SRG-95213

Source

NCI Thesaurus License

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