Cytosine Arabinoside Written by NCI Thesaurus v.07.09d   

Definition of Cytosine Arabinoside An antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, dna replication ceases, specifically during the S phase of the cell cycle. This agent also inhibits DNA polymerase, resulting in a decrease in dna replication and repair. (NCI04) Cytosine Arabinoside is from the group Pyrimidine Antagonist Other Names for Cytosine Arabinoside Cytarabine .beta.-Cytosine arabinoside 1-.beta.-D-Arabinofuranosyl-4-amino-2(1H)pyrimidinone 1-.beta.-D-Arabinofuranosylcytosine 1-Beta-D-arabinofuranosylcytosine 1.beta.-D-Arabinofuranosylcytosine 2(1H)-Pyrimidinone, 4-amino-1.beta.-D-arabinofuranosyl- 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone ARA-cell Alexan Ara-C Arabine Arabinofuranosylcytosine Arabinosylcytosine Aracytidine Aracytin Aracytine Beta-Cytosine Arabinoside CHX-3311 CYTARABINE Cytarabine Hydrochloride Cytarabinum Cytarbel Cytosar Cytosar-U Cytosine Arabinoside Cytosine Arabinosine Hydrochloride Cytosine-.beta.-arabinoside Erpalfa Starasid Tarabine PFS U 19920 U-19920 U-29920A HCl Udicil WR-28453 cytarabine Source NCI Thesaurus License

 

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