Admin

Cephalothin
E-mail
Written by NCI Thesaurus v.07.09d   
Definition of Cephalothin
The sodium salt form of cephalothin, a semisynthetic, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Cephalothin is from the group

Cephalosporin Antibiotic

Other Names for Cephalothin

Cephalothin Sodium
CEPHALOTHIN SODIUM
Keflin

Source

NCI Thesaurus License

 
Tag it:
Delicious
Furl it!
digg
YahooMyWeb
< Prev   Next >
Copyright © 2005 - 2008 Medical Resource Group, LLC. All rights reserved.