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Busulfan
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Written by NCI Thesaurus v.07.09d   
Definition of Busulfan
A synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in dna alkylation and DNA breaks and inhibition of dna replication and RNA transcription. (NCI04)

Busulfan is from the group

Alkylsulfonate Compound

Other Names for Busulfan

Busulfan
1, 4-Bis[methanesulfonoxy]butane
1,4-Bis(methanesulfonoxy)butane
1,4-Bitanediol Dimethanesulfonate Esters
1,4-Butanediol Dimethylsulfonate
1,4-Di(methanesulfonyloxy)butane
1,4-Di(methylsulfonyloxy)butane
BUS
BUSULFAN
Bussulfam
Busulfanum
Busulfex
Busulphan
CB 2041
CB-2041
GT 41
GT-41
Glyzophrol
Joacamine
Methanesulfonic Acid Tetramethylene Ester
Methanesulfonic acid, tetramethylene ester
Mielucin
Misulban
Misulfan
Mitosan
Myeleukon
Myeloleukon
Myelosan
Mylecytan
Myleran
Sulfabutin
Tetramethylene Bis(methanesulfonate)
Tetramethylene bis[methanesulfonate]
WR-19508
busulfan

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