| A halogenated pyrimidine analogue that has been investigated for antineoplastic and radiosensitizing activities. Bromodeoxyuridine competes with thymidine for incorporation into DNA, resulting in DNA mutation and inhibition of cell proliferation. As a radiosensitizer, this agent induces the formation of reactive uracil radicals, resulting in DNA strand breaks and, ultimately, disruption of the cell cycle. (NCI04) Bromodeoxyuridine is from the group Radiosensitizing Agent
Other Names for Bromodeoxyuridine
Bromodeoxyuridine
5-BrdU
5-Bromo-2'-deoxyuridine
5-Bromodeoxyuridine
5-Bromouracil Deoxyriboside
5-Bromouracil deoxyriboside
5-Bromouracil-2-deoxyriboside
5-Budr
BRDU
BrdU
Bromouracil Deoxyriboside
Bromouracil deoxyriboside
Bromouridine
Broxine
Broxuridine
NSC 38297
Neomark
Neomark-BU
broxuridine
Source NCI Thesaurus License
|
Medical Dictionary 
