Written by NCI Thesaurus v.07.09d
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Definition of Antithymocyte Globulin | A purified gamma immunoglobulin with immunosuppressive properties. Obtained from rabbits that have been immunized with human thymocytes, anti-thymocyte globulin specifically recognizes and destroys T lymphocytes. Although the exact mechanism of action is not completely understood, it appears to involve T lymphocyte clearance from the circulation and modulation of T lymphocyte activity. Administering anti-thymocyte globulin with chemotherapy prior to stem cell transplantation may reduce the risk of graft-versus-host disease. (NCI04) Antithymocyte Globulin is from the group Immunosuppressant
Other Names for Antithymocyte Globulin
Anti-Thymocyte Globulin
ATG
ATGAM
ATS
Antithymocyte Globulin
Antithymocyte Serum
Thymoglobulin
antithymocyte globulin
Source NCI Thesaurus License
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